Can Ashwagandha Use Cause Anxiety? (2024)

Not typically, but individual reactions to herbs may vary, and in some cases, ashwagandha might trigger or worsen anxiety.

Ashwagandha (Withania somnifera (L.) Dunal) holds significant importance as a medicinal plant with a history spanning over 3,000 years in Ayurvedic and indigenous medicine. The root has traditionally been used to alleviate stress, enhance strength, and promote overall well-being.

Yet, as with any herbal supplement or medication, individual reactions can vary, and some people might experience unexpected side effects, including anxiety or panic attacks.

While ashwagandha is generally known for its calming properties, it may potentially trigger anxiety in some individuals.

People’s reactions to ashwagandha may vary due to their individual body chemistry. What might relax one person could make another more anxious. In addition, ashwagandha could potentially interact with other medications or supplements, leading to unexpected anxiety.

Can too much ashwagandha cause anxiety?

Ashwagandha is widely known for its ability to reduce stress and anxiety, but excessive consumption of any substance can sometimes lead to unexpected effects, including the worsening of anxiety.

There are some concerns that excessive use of ashwagandha might affect thyroid hormone levels in some individuals, potentially leading to hyperthyroidism (overactive thyroid).

In a case study, a 62-year-old woman in good health used ashwagandha root extract (ARE) for stress relief. She reported no adverse symptoms within the first few weeks of nonregular supplementation, but after 2 months of consistent daily dosing at 1,950 milligrams (mg), she experienced symptoms of thyrotoxicosis (excessive thyroid hormone levels), including worsened anxiety, fatigue, weight loss, “hysteric” behaviors, and other symptoms.

However, it’s important to note that most studies on this topic suggest that ashwagandha may have a beneficial impact on thyroid health by helping to balance thyroid hormone levels, particularly in cases of hypothyroidism (underactive thyroid).

For instance, during an 8-week study, 600 mg of daily ashwagandha root extract led to notable improvements in thyroid hormone levels (TSH, T3, and T4) in people with subclinical hypothyroidism. The treatment effectively normalized these levels over the study period, and only a small percentage of participants (8%) reported mild and temporary adverse effects.

The optimal dosage of ashwagandha may also vary from person to person. Taking more than the recommended dosage might lead to an imbalance in its effects, potentially causing an increase in restlessness and anxiety.

How do I know the right dosage for ashwagandha?

The best way to know how much ashwagandha (or any herbal supplement) is right for you is to discuss it with your primary physician. They’ll be able to advise you on dosage, check for reactions with any of your other medications, and let you know what side effects to expect.

You can also learn more about ashwagandha dosage here.

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While there are no studies suggesting that ashwagandha can cause panic attacks, anecdotal reports suggest they can occur in some individuals.

The positive influence of ashwagandha on mood is partially attributed to its impact on serotonin and GABA. However, just like medications that affect these neurotransmitters, not every individual responds in the same way. So it’s possible it could trigger a panic attack in some people.

Can ashwagandha use cause depression?

Most studies, like this one from 2019, report a reduction in depression after taking ashwagandha; however, not everyone’s body responds in the same way.

Ashwagandha may cause a drop in blood sugar levels. In some cases, this could worsen depressive symptoms, especially for those already dealing with low energy, mental fog, lack of motivation, or occasional depressive states.

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Discontinuing the use of any herb can potentially lead to a temporary increase in anxiety symptoms, especially if the herb was being used to manage stress or anxiety. This phenomenon, known as rebound anxiety, can occur with the abrupt cessation of substances that have been affecting neurotransmitter balance in the brain.

Importantly, however, there are no known studies suggesting that stopping ashwagandha can cause anxiety. In fact, evidence suggests that, as a true adaptogen, ashwagandha doesn’t typically influence body functions more than necessary nor cause withdrawal symptoms.

Research strongly supports ashwagandha’s potential for treating various conditions, particularly anxiety and central nervous system (CNS) disorders.

A 2019 study explored the effects of ashwagandha on stress in adults. Participants took either ashwagandha or a placebo for 60 days. Those who took ashwagandha showed reduced anxiety and stress levels. Hormone levels related to stress also improved.

Learn more about the benefits of ashwagandha here.

Get involved

If you’d like to participate in an ashwagandha study, check out ClinicalTrials.gov, which is maintained by the U.S. National Library of Medicine and provides information about ongoing clinical trials.

You can use keywords like “ashwagandha” or “Withania somnifera” to narrow down your search.

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Ashwagandha is widely considered to be a safe and effective supplement to help relieve anxiety and depression. However, not everyone has the same brain and body chemistry, and all medications and supplements may affect everyone differently.

It’s important to use ashwagandha supplements cautiously and under the guidance of a healthcare professional, especially if you have thyroid or autoimmune issues or are taking medications to lower your blood sugar or blood pressure.

If you’re considering using ashwagandha, it’s recommended that you consult with a healthcare professional to ensure its safe and appropriate use.

Can Ashwagandha Use Cause Anxiety? (2024)

FAQs

Can Ashwagandha Use Cause Anxiety? ›

Ashwagandha is widely known for its ability to reduce stress and anxiety, but excessive consumption of any substance can sometimes lead to unexpected effects, including the worsening of anxiety.

What are the negative side effects to ashwagandha? ›

Safety. In the studies described above and in many other clinical trials, ashwagandha has been well tolerated by participants for up to about 3 months of use. Common side effects are mild and include stomach upset, loose stools, nausea, and drowsiness [7,14].

Does ashwagandha affect the nervous system? ›

Ashwagandha seems to counteract our sympathetic nervous system and decrease the excessive release of stress hormones, helping our bodies to cope with stress and come back into balance. Cortisol has a circadian rhythm, tending to go up in the early morning and decrease throughout the day.

What happens when you stop taking ashwagandha? ›

Ashwagandha withdrawal is rare, but some people may experience mild symptoms such as insomnia, brain fog, and headaches after stopping taking the supplement. These symptoms are thought to be caused by a change in GABA levels in the brain.

Can you feel effects of ashwagandha? ›

Some studies find that it takes weeks of ashwagandha use at high dosages to reduce stress and anxiety. But Parrish said that, depending on the dosage, some people may feel the effects within days. “It's very tonifying for a nervous system.

Can ashwagandha cause anxiety? ›

Quick answer: Can ashwagandha cause anxiety? While ashwagandha is generally known for its calming properties, it may potentially trigger anxiety in some individuals. People's reactions to ashwagandha may vary due to their individual body chemistry. What might relax one person could make another more anxious.

Why you shouldn't take ashwagandha everyday? ›

The long-term safety of ashwagandha is not known. Large doses of ashwagandha might cause stomach upset, diarrhea, and vomiting. Rarely, liver problems, including severe liver failure and a need for liver transplantation, might occur.

Is brain fog a side effect of ashwagandha? ›

Ashwagandha Boosts GABA, Combating Stress and Worry

Stress and worry are often treated by stimulating the receptors for a neurotransmitter called GABA (gamma aminobutryric acid). However, many GABA stimulators have side effects of fatigue and brain fog.

How quickly does ashwagandha work for anxiety? ›

Taking ashwagandha for at least two months is recommended to enjoy full anti-anxiety benefits. In summary, the timeline for various benefits can range from 7 to 90 days. Immediately, you may experience reductions in cortisol levels, blood pressure,, and sugar concentrations and improved sleep if a sleep aid is used.

What medications should not be taken with ashwagandha? ›

There is evidence that ashwagandha might interact with some medications, including those for diabetes and high blood pressure, medicines that decrease the immune system response (immunosuppressants), sedatives, anti-seizure medications (anticonvulsants), and thyroid hormone medications.

Can you lose feelings from ashwagandha? ›

These ashwagandha side effects include an emotionally blunt affect—feeling flat and emotionally numb. In general, ashwagandha should be used like any other mental health medication.

Why should you cycle off of ashwagandha? ›

Preserve Sensitivity and Efficacy: Using Ashwagandha all the time can make your body less responsive. Cycling it keeps your body sensitive to its effects. This way, you keep getting the full benefits. Avoid Tolerance and Dependency: Frequent breaks prevent your body from getting used to a dose.

Can ashwagandha cause heart palpitations? ›

In rare cases, ashwagandha has been shown to cause liver disease, heart palpitations, and allergic reactions. It's important to check in with your doctor to make sure this supplement is the right choice for you.

Why do I feel weird on ashwagandha? ›

As mentioned above, ashwagandha can cause a rapid drop in blood sugar levels, and low blood sugar symptoms can both mirror and increase the intensity of anxiety. An increased heart rate, racing mind, shakiness, irritability, and panic are all symptoms that can intensify due to low blood sugar.

What is the best vitamin for stress and anxiety? ›

9 Best Vitamins for Stress Relief
  • Vitamin B Complex. B vitamins are linked to brain health, stress reduction, reduced feelings of anxiety or depression, and more. ...
  • Vitamin D. Vitamin D is mainly associated with sunlight exposure. ...
  • Vitamin C. ...
  • Omega-3. ...
  • Ashwagandha. ...
  • L-Theanine. ...
  • Rhodiola Rosea. ...
  • Melatonin.
Aug 29, 2023

How long does ashwagandha take to wear off? ›

How long will ashwagandha remain in my system? There are two types of compounds in ashwagandha—fat-soluble and water-soluble. The water-soluble compounds leave your body between 2-3 days, while the fat-soluble ones may take a month to leave your body.

Can ashwagandha cause negative thoughts? ›

The Ayurvedic energy of ashwagandha is “heating,” meaning it tends to increase inflammation as well as “hot” emotions such as irritation and frustration — both of which contribute to anxiety.

What supplements should not be taken with ashwagandha? ›

Are there interactions with herbs and supplements? Ashwagandha might lower blood pressure. Taking it with other supplements that have the same effect might cause blood pressure to drop too much. Examples of supplements with this effect include andrographis, casein peptides, L-arginine, niacin, and stinging nettle.

Can ashwagandha cause weight gain? ›

Can ashwagandha make you gain weight? Ashwagandha is unlikely to make you gain weight. There's some chance it could help you lose weight, but weight loss is a complicated formula. It's not clear if or how ashwagandha might play a role, but if it does, it likely has something to do with your metabolism.

Is ashwagandha safe effective? ›

Generally speaking, ashwagandha is safe for most people though some get headaches and nausea. Given your chronic stress, there is some evidence to support using ashwagandha. In fact, this is the area in which the plant has been studied the most.

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