ELDERBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

Overview

Elderberry (Sambucus nigra) is the dark purple berry from the European elder tree. It has a long history of use for cold and flu.

Elderberry is a popular ingredient in supplements. It might affect the immune system, and also seems to have activity against viruses, including the flu.

Elderberry is commonly used for the common cold, flu, high cholesterol, and many other conditions, but there is no good scientific evidence to support most of these uses, with the possible exception of the flu. There is also no good evidence to support using elderberry for COVID-19.

Don't confuse elderberry with American Elder, Elderflower, or Dwarf Elder. These aren't the same and have different effects.

Uses & Effectiveness ?

Possibly Effective for

  • Flu (influenza). Taking a specific elderberry extract syrup (Sambucol, Nature's Way) seems to reduce flu symptoms when taken within 48 hours of the first symptoms. But it might not be helpful in some people, including those with lung conditions or children under 12 years of age.

There is interest in using elderberry for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.

Side Effects

When taken by mouth: Elderberry is commonly consumed in foods. Elderberry extract is possibly safe when taken for up to 12 weeks. There isn't enough reliable information to know if it is safe to use for longer than 12 weeks.

It is possibly unsafe to consume elder leaves or stems, or unripe or uncooked elderberries. Cooked elderberry seems to be safe, but raw and unripe fruit might cause nausea, vomiting, or severe diarrhea.

Special Precautions and Warnings

When taken by mouth: Elderberry is commonly consumed in foods. Elderberry extract is possibly safe when taken for up to 12 weeks. There isn't enough reliable information to know if it is safe to use for longer than 12 weeks.

It is possibly unsafe to consume elder leaves or stems, or unripe or uncooked elderberries. Cooked elderberry seems to be safe, but raw and unripe fruit might cause nausea, vomiting, or severe diarrhea. Children: Elderberry extract is possibly safe in children 5 years of age or older when taken by mouth for up to 3 days. There isn't enough reliable information to know if it is safe for children younger than 5 years of age to take elderberry. Unripe or uncooked elderberries are possibly unsafe. Don't give them to children.

Pregnancy and breast-feeding: There isn't enough reliable information to know if elderberry extract is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

"Autoimmune diseases" such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Elderberry might cause the immune system to become more active. This could increase the symptoms of autoimmune diseases. If you have one of these conditions, it's best to avoid using elderberry.

Interactions ?

    Moderate Interaction

    Be cautious with this combination

  • Medications that decrease the immune system (Immunosuppressants) interacts with ELDERBERRY

    Elderberry can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking elderberry along with these medications might decrease the effects of these medications.

Dosing

Elderberry fruit extracts have most often been used by adults in doses up to 1200 mg by mouth daily for 2 weeks. Elderberry is available in many different types of products, including syrups and mouth rinses. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

Don't consume green, unripe, uncooked elderberries. They contain toxins and can be poisonous.

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CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circ*mstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you.

This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.
© Therapeutic Research Faculty 2020.

ELDERBERRY: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (2024)

FAQs

What are the precautions for elderberries? ›

DO NOT use unripe or uncooked elderberries. They may be poisonous. Elderberry appears to have few side effects when used properly for short periods of time (up to 5 days). Pregnant and breastfeeding women should not take elderberry.

What are the negative side effects of elderberry? ›

The common side effects of taking raw elderberry plant products, such as fruit, flower, leaves, bark, or root include:
  • Stomach problems.
  • Nausea and vomiting.
  • Diarrhea and constipation.

Does elderberry have any drug interactions? ›

Elderberry has no known severe, serious, or moderate interactions with other drugs. Elderberry has mild interactions with at least 28 different drugs.

Which autoimmune diseases should avoid elderberry? ›

People who have autoimmune conditions such as multiple sclerosis (MS), rheumatoid arthritis, lupus, psoriasis, and inflammatory bowel disease should not use elderberry. Elderberry may boost the immune system, which can worsen autoimmune diseases. Many autoimmune disorders require immunosuppressant drugs.

What is elderberry used for? ›

Elderberry is the dark purple berry of the European or black elder tree, which grows in the warmer parts of Europe, North America, Asia, and Northern Africa. Elderberry has been used in folk medicine to treat colds and flu. Elderberry is promoted as a dietary supplement for colds, flu, and other conditions.

How to safely use elderberries? ›

Some varieties of elderberries can be toxic when eaten raw – the best way to avoid this is to make sure you always cook your elderberries well first. There are recipes that use raw elderberries but these are best avoided.

Who should not take elderberry? ›

People who have an allergy to elder pollen might react to elderberry supplements. If you have diabetes, multiple sclerosis, lupus, or rheumatoid arthritis, talk to your doctor before taking elderberry.

Why is elderberry not FDA approved? ›

Another thing to keep in mind? Elderberry is not FDA-approved because it's regulated as a supplement, not a drug. The U.S. Food and Drug Administration (FDA) isn't required to approve a supplement prior to sale and companies manufacturing them are responsible for their safety and labeling them properly.

Does elderberry affect your kidneys? ›

Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks.

Should seniors take elderberry? ›

Research hasn't concluded whether elderberry supplements are suitable for long-term use for more than 12 weeks. Elderberry supplements are usually safe for adults, including seniors.

Do doctors recommend elderberry? ›

Opinions vary on whether elderberry is helpful, but most doctors believe it's safe to have in small doses. But unripe or uncooked berries or flowers from the plant can cause nausea, vomiting, and diarrhea. Larger amounts can cause even more serious poisoning.

What does elderberry do to the liver? ›

However, another study in mice with high cholesterol found that a diet including black elderberry reduced the amount of cholesterol in the liver and aorta but not the blood ( 24 ). Further studies found that rats that were fed foods containing polyphenols extracted from elderberry had reductions in blood pressure (25).

How do you remove toxins from elderberries? ›

To neutralize toxins, specifically cyanide-inducing glycosides, heat treatment is a must. Boiling elderberries for at least 30 minutes is the go-to method. This ensures the destruction of harmful compounds. Steaming or baking can also do the trick, as long as the berries reach a high enough temperature.

How safe is elderberry? ›

Opinions vary on whether elderberry is helpful, but most doctors believe it's safe to have in small doses. But unripe or uncooked berries or flowers from the plant can cause nausea, vomiting, and diarrhea. Larger amounts can cause even more serious poisoning.

How do you remove cyanide from elderberries? ›

Simmer it for about 20 minutes; this should be enough to break down the cyanogenic compounds. But remember, you need to stir them occasionally to ensure even heat distribution. After cooking, strain the mixture using a fine-mesh sieve.

How do you protect elderberries? ›

Cherries, strawberries, blueberries and elderberries are just some of the berry crops that birds love. Here are some ideas on preventing the damage. Bird netting is the most common protective device. Consider placing some tall stakes and a framework over the plant and then draping the netting over the stakes.

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