Why Women Worry: How Hormones Affect Anxiety and What We Can Do About It (2024)

Published 03.23.2021 @ 3:43 pm

By Rebecca Schnatz DO, FACOG

Dr. Rebecca Schnatz helps us understand the causes of anxiety and tips for finding relief.

We have surpassed the one-year mark of the COVID-19 pandemic, and I want to take the opportunity to discuss something many people have been dealing with a lot over the past year: anxiety. I’ve noticed a profound increase in anxiety, depression, and mood concerns due to the COVID-19 pandemic, with varied effects on women’s lives. But there is also a lot that happens within a woman’s body that can contribute to anxiety.

As a women’s health professional, I spend a large amount of my time with patients discussing the various aspects of female hormones and their effects on day-to-day life. Having a better understanding of how hormones affect our worries and perhaps finding ways to control them may be especially helpful these days. Let’s take a look.

Anxiety can be induced during times of hormonal change

With regard to women’s health, anxiety is the most commonly diagnosed psychiatric disease, affecting nearly one in three women in their lifetime. Many women experience reproductive cycle mood symptoms during times of hormonal changes. These include premenstrual symptoms (PMS), postpartum “blues” and perimenopausal mood changes.These symptoms, although apparent, are not typically pathologic and are often transient.Should they evolve into more severe symptoms, patients may be experiencing premenstrual dysphoric disorder (PMDD), postpartum depression or anxiety, or a mood disorder outside the reproductive realm such as major depressive disorder or bipolar disorder.

Some of the specific hormones that play a role in increased or decreased levels of anxiety are estrogen, progesterone, testosterone, oxytocin, and stress steroids such as cortisol and adrenaline. The drop in estrogen and progesterone that occurs at the end of a women’s menstrual cycle may cause anxiety and other mood symptoms. This is similar to the drop experienced during perimenopause, the time during which your body makes the natural transition to menopause. Low levels of testosterone have also been linked to elevated worry or panic. Oxytocin, on the other hand, has been shown to reduce stress and anxiety.

The vicious cycle of anxiety and hormones

Your bodyproduces stress hormones(cortisol andadrenaline)in response to a threat or fear,(eitherrealor perceived.)These steroid hormoneshelp you cope and prepare for action.Ifthere is nothing to act on, you are left feeling anxious.Not only does stress hormone productioncause anxiety in and of itself,but itcandecreaseproductionoftestosterone, which can alsocauseanxiety.And since testosteronepartiallycontrols the release of cortisol,loweredtestosterone levelscan set off a rise in cortisolproduction. Thecombined effectis a viciouscycleof anxiety.

Behavioral changes can help you manage and prevent anxiety

Although it may come as no surprise, behavioral lifestyle changes are the first step to better controlling anxiety. Hormonal influences may make this difficult at certain times, but healthy changes will never hurt. Increasing sleep quality, reducing abuse of substances, and reducing stressors are helpful ways to cope with anxiety and depression symptoms. Exercise (especially yoga), limiting caffeine intake, smoking cessation, limiting alcohol use, meditation and relaxation have also been shown to be effective modalities.

There are also things you can do to boost production of oxytocin, the hormone that helps reduce stress and anxiety. Outside of childbearing, oxytocin is released during contact with loved ones and promotes relaxation and trust. Natural ways to boost oxytocin include showing generosity toward others, cuddling with a loved one, and petting an animal.

Ways your health care professional can help

Sometimes you may need more than behavioral changes to get relief from your anxiety. Talking with your healthcare professional will help determine if the symptoms you’re experiencing warrant psycho and pharmacologic therapy. Hormonal therapy is not approved to treat anxiety specifically, but a combination approach may be something to explore. Women also respond differently to hormonal birth control and can discuss contraception options with their OB/GYN.

Anxiety is a vast women’s health topic, and I have merely scratched the surface. Be sure to talk with your healthcare professional about any concerns you may have with how to manage elevated anxiety. We are always here to help!

To schedule an appointment with a VPFW provider, you can call us at804-897-2100orset anappointment online.

Why Women Worry: How Hormones Affect Anxiety and What We Can Do About It (2024)

FAQs

Which female hormone causes anxiety? ›

The drop in estrogen and progesterone that occurs at the end of a women's menstrual cycle may cause anxiety and other mood symptoms. This is similar to the drop experienced during perimenopause, the time during which your body makes the natural transition to menopause.

How to help hormonal anxiety? ›

How to Reduce Hormone-Related Anxiety
  1. Exercise daily.
  2. Manage your stress through relaxation techniques like meditation and yoga.
  3. Practice a healthy diet with fiber-rich foods, fermented foods, and essential vitamins like omega-3s.
  4. Drink plenty of water. ...
  5. Get enough sleep.

Does estrogen calm anxiety? ›

Estrogen. Estrogen is known to calm the fear response in women. 3 Specifically, research has shown that women trained on a fear-extinction task do better when the level of estrogen in their blood is higher.

How do you fix hormone imbalance? ›

How to Naturally Balance Your Hormones
  1. Get enough protein. Proteins provide amino acids that your body cannot make on its own and are needed to produce peptide hormones. ...
  2. Exercise regularly. ...
  3. Maintain a moderate weight. ...
  4. Watch your gut health. ...
  5. Lower sugar intake. ...
  6. Reduce stress. ...
  7. Get enough sleep. ...
  8. Eat healthy fats.

How to know if estrogen is low? ›

Signs of low estrogen include:
  • Dry skin.
  • Tender breasts.
  • Weak or brittle bones.
  • Trouble concentrating.
  • Moodiness and irritability.
  • vagin*l dryness or atrophy.
  • Hot flashes and night sweats.
  • Irregular periods or no periods (amenorrhea).
Feb 8, 2022

What drink increases estrogen? ›

Red wine may contain higher levels of phytoestrogens due to its fermentation process. Beer also contains phytoestrogens, and its effect can be seen even with moderate intake. Hard liquor is metabolized faster than beer or wine, so it may have a more immediate effect on estrogen levels.

Does vitamin D increase estrogen? ›

On the other hand, vitamin D has been shown to downregulate in immune cells the expression of aromatase, which converts testosterone to estrogen, leading to a decrease in estrogen level.

Does vitamin B12 increase estrogen? ›

B vitamins play an important role in the creation and activation of estrogen in the body. Low levels of these vitamins can lead to reduced levels of estrogen.

What hormone makes you relax? ›

Serotonin: Dubbed the "feel-good hormone," serotonin plays a key role in staving off anxiety and depression. In fact, the main class of drugs used to treat these conditions — SSRIs (selective serotonin reuptake inhibitors) — increase serotonin levels in the brain.

What imbalance causes anxiety? ›

Epinephrine is just one chemical involved in your body's response to anxiety. Other chemicals may also play a role. For example, a serotonin imbalance¹ may contribute to anxiety, as can high cortisol levels. However, epinephrine is the primary chemical because it is directly involved in your anxiety symptoms.

Which hormone is responsible for fear and anxiety? ›

Hormones of the HPA axis, such as Cortisol, or corticosterone (in rodents), ACTH, and CRF are usually increased in a state of fear and anxiety. They also appear to modulate the response to threatening events.

Which hormone is responsible for anxiety? ›

The primary hormone related to anxiety is cortisol. You might have heard people mention cortisol before, referring to it as the “stress” hormone. This is because cortisol levels are elevated during prolonged periods of stress.

What chemical imbalance causes anxiety? ›

Epinephrine is just one chemical involved in your body's response to anxiety. Other chemicals may also play a role. For example, a serotonin imbalance¹ may contribute to anxiety, as can high cortisol levels. However, epinephrine is the primary chemical because it is directly involved in your anxiety symptoms.

Does progesterone increase anxiety? ›

Progesterone, the female sex hormone, stimulates the part in the brain that is responsible to your fight-or-flight responses and may trigger your anxiety.

What hormone increases stress and anxiety? ›

Cortisol, the primary stress hormone, increases sugar, also called glucose, in the bloodstream, enhances the brain's use of glucose and increases the availability of substances in the body that repair tissues. Cortisol also slows functions that would be nonessential or harmful in a fight-or-flight situation.

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